Tropical Doctor > Volume 39, Number 4 > Pp. 233-235

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Short Reports

Neurobrucellosis: an evaluation of a rare presentation of brucellosis from a tertiary care centre in Central Anatolia, Turkey

Hayati Demiraslan MD   ^*   Gokhan Metan MD   ^*    Emine Alp Mee MD   ^*   Orhan Yildiz MD   ^*   Bilgehan Aygen MD   ^*   Bulent Sumerkan MD      Mehmet Doganay MD   ^*

^* Department of Infectious Diseases and Clinical Microbiology; Department of Microbiology and Clinical Microbiology, Erciyes University, Faculty of Medicine, Tp Fakultesi, Gevher Nesibe Hastanesi, Enfeksiyon Hastaliklari Klinigi, Kat: 10, Melikgazi, 38039 Kayseri, Turkey

Correspondence to: Gokhan Metan, Department of Infectious Diseases and Clinical Microbiology, Erciyes University, Faculty of Medicine, Tp Fakultesi, Gevher Nesibe Hastanesi, Enfeksiyon Hastaliklari Klinigi, Kat: 10, Melikgazi, 38039 Kayseri, Turkey Email: gokhanmetan{at}gmail.com, gmetan{at}erciyes.edu.tr

Nervous system involvement is a rare manifestation of brucellosis. We describe our experience of the diagnosis, treatment and final outcome of patients with neurobrucellosis at the Erciyes University Gevher Nesibe Hospital, a tertiary referral centre in Central Anatolia, Turkey. Thirty-six adult patients were diagnosed with neurobrucellosis from January 1997 to December 2006. Headache and fever were the most common symptoms. Neck stiffness was present in 25 patients. Brucella spp was isolated from the blood of nine patients and from the cerebrospinal fluid of 11. Doxycycline (by mouth) plus rifampin (by mouth) with ceftriaxone (intravenously) were the most common treatment choices. Three patients died as a result of problems other than neurobrucellosis and relapse occurred in one patient. Neurobrucellosis presents with hetoregenous clinical signs.

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