Tropical Doctor > Volume 38, Number 4 > Pp. 241-243

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Short Reports

A study of clinico-haematological profiles of pancytopenia in children

V Gupta MD DNB   ^*    S Tripathi MD   ^*   V Tilak MD      B D Bhatia MD FAMS   ^*

^* Department of Pediatrics; Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India

Correspondence to: Dr Vineeta Gupta, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India Email: vineetaguptabhu{at}gmail.com

We report on the clinico-haematological profile of pancytopenia in children from the Departments of Pediatrics and Pathology, Institute of Medical Sciences, Banaras Hindu University, India, over a period of 30 months. Pancytopenia was defined as: haemoglobin <10 g/dL, absolute neutrophil count 1.5 x 10⁹/L and platelet count <100 x 10⁹/L. A detailed history, clinical examination and haematological parameters were recorded. Bone marrow aspiration and trephine biopsy were carried out in all cases. One hundred and five cases aged 1.5–18 years, with a mean age of 8.6 years, were included in the study. Aplastic anaemia was the most common cause of pancytopenia (43%) followed by acute leukaemia (25%). Infections were the third most common cause of pancytopenia of which kala azar was the most common. Megaloblastic anaemia was seen in 6.7%.

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