Tropical Doctor > Volume 38, Number 2 > Pp. 91-93

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Tanrikulu, A C. Articles by Gurkan, F. Search for Related Content PubMed PubMed Citation Social Bookmarking                      What's this?

Articles

Risk factors for drug resistant tuberculosis in southeast Turkey

A Cetin Tanrikulu ^*    Salih Hosoglu    Tuncer Ozekinci    Abdurrahman Abakay    Fuat Gurkan ^¶

^* Department of Chest Diseases, School of Medicine, Kafkas University, Kars 36110, Turkey; Department of Infectious Diseases, Dicle University Hospital, Diyarbakir 21100, Turkey; Department of Clinical Microbiology, Dicle University Hospital, Diyarbakir 21100, Turkey; Tuberculosis Control Dispensary, Diyarbakir 21100, Turkey; ^¶ Department of Pediatry, Dicle University Hospital, Diyarbakir 21100, Turkey

Correspondence to: A Cetin Tanrikulu, Department of Chest Diseases, School of Medicine, Kafkas University, Kars, Turkey Email: cetintanrikulu{at}hotmail.com

We undertook a cross-sectional survey of 116 patients at Dicle Hospital, Turkey, who had with bacteriologically confirmed tuberculosis (TB). Demographic and clinical features, including age, gender, pulmonary TB history, associated diabetes mellitus, previous TB treatment, residential area and education, were collected from charts. Eighty-four of the strains were found to be susceptible to all drugs. The resistance to one or more drug(s) was found in 32 strains. Multi-drug resistant (MDR) TB was found in 13 strains (11.3% of the total and 40.7% of the drug resistant strains). The resistance to isoniazid was the most frequently seen (25 strains, 21.5%). In the multivariable analysis, only previous TB treatment (P = 0.000) remained a significant predictor for drug resistance; in MDR, previous TB treatments (P = 0.002) remained significant in the final model. The patient's educational status was found to be negatively correlated with the risk of MRD-TB (P = 0.035). Previous TB treatment and low educational status were found to important risk factors for the development of MDR-TB.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?