Tropical Doctor > Volume 38, Number 2 > Pp. 113-116

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Blanke, C. H Articles by Müller, M. S Search for Related Content PubMed PubMed Citation Social Bookmarking                      What's this?

Short Reports

Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial

Christoph H Blanke MD DTMH   ^*    Godson B Naisabha ^*   Mussa B Balema ^*   Godfrey M Mbaruku PhD      Lutz Heide PhD      Markus S Müller MD DTMH   

^* Matyazo Health Centre, Diocese of Western Tanganyika, PO Box 1054, Kigoma, Tanzania; Regional Medical Office, Kigoma Region, PO Box 16, Kigoma, Tanzania; Department of Pharmaceutical Biology, Pharmaceutical Institute, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; German Institute for Medical Mission, Paul-Lechler-Str. 24, 72076 Tübingen, Germany

Correspondence to: Dr Christoph H Blanke, Matyazo Health Centre, Diocese of Western Tanganyika, Kigoma, Tanzania Email: christophblanke{at}yahoo.com

Tea preparations from the herb Artemisia annua L. (Aa) which is used in traditional Chinese medicine might offer an inexpensive way of producing artemisinin drugs locally. We compared Aa with sulfadoxine-pyrimethamine (SP) in the treatment of uncomplicated falciparum malaria in semi-immune adults. After seven days, the cure rate was 7/10 for the Aa compared to 7/9 for SP; this dropped to 4/10 for Aa and 4/9 for SP at day 14 and to 1/9 for Aa and 3/8 for SP at day 28.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?