Tropical Doctor > Volume 38, Number 1 > Pp. 28-30

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Faridi, M M A Articles by Sarafrazul, A. Search for Related Content PubMed PubMed Citation Social Bookmarking                      What's this?

Short Reports

Clinical and biochemical profile of dengue haemorrhagic fever in children in Delhi

M M A Faridi MNAMS FIAP      Anju Aggarwal MD MNAMS     Manish Kumar MD     Abedin Sarafrazul MD  

Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, New Delhi 110095, India

Correspondence to: Dr M M A Faridi, Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, E-11, GTB Hospital Campus, New Delhi 110095, India Email: mmafaridi{at}yahoo.co.in

The clinical and biochemical profile of dengue haemorrhagic fever (DHF) varies from epidemic to epidemic. We studied children hospitalized with DHF from September 2003 to December 2003. All were diagnosed, managed and monitored according to a standard protocol. Of the 34 who fulfilled the World Health Organization criteria of DHF, 22 (64.6%) were male. All patients presented with fever and hepatomegaly. Examination also revealed splenomegaly in 11 (32.4%), ascites in 6 (17.6%) and pleural effusion in 3 (8.8%). Common bleeding manifestations were positive tourniquet test in 22 (64.7%) and epistaxis in eight (23.5%). Most children had a platelet count of between 20,000/mm³ and 50,000/mm³ (56%). Bleeding manifestations were not related to platelet count (P > 0.05). Serum glutamic pyruvic transaminase (SGPT) >40 IU/L was seen in 22 (64.6%) patients, alkaline phosphate (ALP) >400 IU/L in 12 (35.3%) and serum bilirubin >1 mg% in 3 (8.8%). IgM dengue serology was positive in 68.5% cases. There was no significant difference in liver function tests with age or sex (P > 0.05). Clinical features of DHF varied from the previous epidemic. Hepatic dysfunction with increased levels of serum enzymes was common in DHF.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?